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The Brain on Ketamine: What Happens During a Session & What Studies Say

The Brain on Ketamine: What Happens During a Session & What Studies Say

At The Re/ Clinic, we’re always exploring the most innovative treatments to support mental wellness. One therapy gaining significant attention is ketamine-assisted therapy, particularly for patients struggling with treatment-resistant depression, anxiety, and PTSD. But how exactly does ketamine affect the brain? And what do clinical studies reveal about its potential? Let’s dive in.

What Happens During a Ketamine Session?

During a ketamine session at The Re/ Clinic, patients receive a carefully controlled dose of ketamine, typically administered via IV infusion. Each session lasts around 40 to 60 minutes, with close supervision by our trained medical team to ensure safety and comfort.

Patients often experience a dissociative state, where they feel detached from their surroundings and sense of self. Many describe this as a “reset” or “lifting of mental fog.” Visual distortions, deep introspection, and heightened emotional awareness are common, making it easier to process trauma, reframe negative thoughts, and foster healing.

After the session, patients are encouraged to engage in integration practices, such as journaling or therapy, to solidify insights gained during treatment.

How Does Ketamine Affect the Brain?

Ketamine primarily acts on the NMDA receptors in the brain, modulating the neurotransmitter glutamate. This unique mechanism leads to:

  • Increased neuroplasticity: Ketamine promotes the growth of new neural connections, helping the brain “rewire” negative thought patterns.
  • Reduction of inflammation: Some studies suggest ketamine reduces brain inflammation linked to depression.
  • Rapid antidepressant effects: Unlike traditional antidepressants, which can take weeks to work, ketamine has shown to produce immediate improvements in mood and anxiety.

What Do the Studies Say?

Several studies highlight ketamine’s efficacy:

  • 2023 Harvard-led study found ketamine produced significant improvement in 55% of patients with treatment-resistant depression, often within hours.
  • Research shows ketamine enhances the brain’s neuroplasticity, making it easier for patients to adopt healthier coping mechanisms.
  • Multiple trials confirm ketamine’s potential for conditions like PTSD, anxiety, and chronic pain, providing new hope for those unresponsive to conventional treatments.

Is Ketamine Therapy Right for You?

At The Re/ Clinic, we offer personalized ketamine protocols, ensuring each patient receives tailored care. If you’ve struggled with depression, anxiety, or trauma and traditional treatments haven’t worked, ketamine therapy may be a transformative option.

Ready to explore ketamine-assisted therapy? Contact The Re/ Clinic in Sandy, UT, to schedule a consultation and learn how we can support your mental wellness journey.

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